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Critical role of histone H3 lysine 27 demethylase Kdm6b in the homeostasis and function of medullary thymic epithelial cells

Medullary thymic epithelial cells (mTECs) play a central role in the establishment of T cell central immunological tolerance by promiscuously expressing tissue-restricted antigens (TRAs) and presenting them to developing T cells, leading to deletion of T cells responding to self-antigens. However, m...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Liu, Zhi, Zhang, Haohao, Hu, Yiming, Liu, Dandan, Li, Lingling, Li, Cuifeng, Wang, Qi, Huo, Junhaohui, Liu, Hanshao, Xie, Ningxia, Huang, Xingxu, Liu, Yongzhong, Chen, Charlie Degui, Shi, Yufang, Zhang, Xiaoren
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493893/
https://ncbi.nlm.nih.gov/pubmed/32346138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0546-8
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