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Immediate Inhibition of Spinal Secretory Phospholipase A(2) Prevents the Pain and Elevated Spinal Neuronal Hyperexcitability & Neuroimmune Regulatory Genes that Develop with Nerve Root Compression
Cervical nerve root injury induces a host of inflammatory mediators in the spinal cord that initiate and maintain neuronal hyperexcitability and pain. Secretory phospholipase A(2) (sPLA(2)) is an enzyme that has been implicated as a mediator of pain onset and maintenance in inflammation and neural i...
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| Опубликовано в: : | Neuroreport |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7493813/ https://ncbi.nlm.nih.gov/pubmed/32881777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000001520 |
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