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Immediate Inhibition of Spinal Secretory Phospholipase A(2) Prevents the Pain and Elevated Spinal Neuronal Hyperexcitability & Neuroimmune Regulatory Genes that Develop with Nerve Root Compression

Cervical nerve root injury induces a host of inflammatory mediators in the spinal cord that initiate and maintain neuronal hyperexcitability and pain. Secretory phospholipase A(2) (sPLA(2)) is an enzyme that has been implicated as a mediator of pain onset and maintenance in inflammation and neural i...

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Detaylı Bibliyografya
Yayımlandı:Neuroreport
Asıl Yazarlar: Quindlen-Hotek, Julia C., Kartha, Sonia, Winkelstein, Beth A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493813/
https://ncbi.nlm.nih.gov/pubmed/32881777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000001520
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