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Ablating spinal NK1-bearing neurons eliminates the development of pain & reduces spinal neuronal hyperexcitability & inflammation from mechanical joint injury in the rat

The facet joint is a common source of pain especially from mechanical injury. Although chronic pain is associated with altered spinal glial and neuronal responses, the contribution of specific spinal cells to joint pain are not understood. This study used the neurotoxin [Sar(9),Met(O(2))(11)]-substa...

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Detalhes bibliográficos
Main Authors: Weisshaar, Christine L., Winkelstein, Beth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972292/
https://ncbi.nlm.nih.gov/pubmed/24389017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.12.003
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