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Gabapentin alleviates facet-mediated pain in the rat through reduced neuronal hyperexcitability and astrocytic activation in the spinal cord

Although joint pain is common, its mechanism(s) remain undefined, with little known about the spinal neuronal responses that contribute to this type of pain. Afferent activity and sustained spinal neuronal hyperexcitability correlate to facet joint loading and the extent of behavioral sensitivity in...

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Detalhes bibliográficos
Main Authors: Dong, Ling, Crosby, Nathan D., Winkelstein, Beth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849122/
https://ncbi.nlm.nih.gov/pubmed/24094695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.07.016
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