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Spinal astrocytic thrombospondin-4 induced by excitatory neuronal signaling mediates pain after facet capsule injury
Thrombospondin-4 (TSP4) is a synaptogenic molecule that is upregulated in the spinal cord after painful facet joint injury and may contribute to spinal hyperexcitability. However, the mechanisms leading to increased spinal TSP4 are unclear. Because primary afferent activity is critical in the develo...
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| Publié dans: | Ann Biomed Eng |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096960/ https://ncbi.nlm.nih.gov/pubmed/27160673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-016-1639-x |
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