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Association Between a Variable Number Tandem Repeat Polymorphism Within the DAT1 Gene and the Mesolimbic Pathway in Parkinson's Disease

The loss of ventral striatal dopaminergic neurons in Parkinson's disease (PD) predicts an impact on the reward system. The ventrostriatal system is involved in motivational processing and its dysfunction may be related to non-motor symptoms such as depression and apathy. We previously documente...

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Bibliografski detalji
Izdano u:Front Neurol
Glavni autori: du Plessis, Stefan, Bekker, Minke, Buckle, Chanelle, Vink, Matthijs, Seedat, Soraya, Bardien, Soraya, Carr, Jonathan, Abrahams, Shameemah
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493621/
https://ncbi.nlm.nih.gov/pubmed/32982958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.00982
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