Mitochondrial Targeting of the Enteropathogenic Escherichia coli Map Triggers Calcium Mobilization, ADAM10-MAP Kinase Signaling, and Host Cell Apoptosis

The ability of diarrheagenic bacterial pathogens, such as enteropathogenic Escherichia coli (EPEC), to modulate the activity of mitogen-activated protein kinases (MAPKs) and cell survival has been suggested to benefit bacterial colonization and infection. However, our understanding of the mechanisms...

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Veröffentlicht in:mBio
Hauptverfasser: Ramachandran, Rachana Pattani, Spiegel, Chaya, Keren, Yael, Danieli, Tsafi, Melamed-Book, Naomi, Pal, Ritesh Ranjan, Zlotkin-Rivkin, Efrat, Rosenshine, Ilan, Aroeti, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492733/
https://ncbi.nlm.nih.gov/pubmed/32934081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01397-20
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