Enteropathogenic Escherichia coli remodels host endosomes to promote endocytic turnover and breakdown of surface polarity

Enteropathogenic E. coli (EPEC) is an extracellular diarrheagenic human pathogen which infects the apical plasma membrane of the small intestinal enterocytes. EPEC utilizes a type III secretion system to translocate bacterial effector proteins into its epithelial hosts. This activity, which subverts...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Kassa, Ephrem G., Zlotkin-Rivkin, Efrat, Friedman, Gil, Ramachandran, Rachana P., Melamed-Book, Naomi, Weiss, Aryeh M., Belenky, Michael, Reichmann, Dana, Breuer, William, Pal, Ritesh Ranjan, Rosenshine, Ilan, Lapierre, Lynne A., Goldenring, James R., Aroeti, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615643/
https://ncbi.nlm.nih.gov/pubmed/31242273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007851
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