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Enteropathogenic Escherichia coli remodels host endosomes to promote endocytic turnover and breakdown of surface polarity

Enteropathogenic E. coli (EPEC) is an extracellular diarrheagenic human pathogen which infects the apical plasma membrane of the small intestinal enterocytes. EPEC utilizes a type III secretion system to translocate bacterial effector proteins into its epithelial hosts. This activity, which subverts...

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Publié dans:PLoS Pathog
Auteurs principaux: Kassa, Ephrem G., Zlotkin-Rivkin, Efrat, Friedman, Gil, Ramachandran, Rachana P., Melamed-Book, Naomi, Weiss, Aryeh M., Belenky, Michael, Reichmann, Dana, Breuer, William, Pal, Ritesh Ranjan, Rosenshine, Ilan, Lapierre, Lynne A., Goldenring, James R., Aroeti, Benjamin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615643/
https://ncbi.nlm.nih.gov/pubmed/31242273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007851
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