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Antigen-Specific CD4(+) T Cells Exhibit Distinct Kinetic and Phenotypic Patterns During Primary and Secondary Responses to Infection

Although CD4(+) T cell memory is a critical component of adaptive immunity, antigen-specific CD4(+) T cell recall responses to secondary infection have been inadequately studied. Here we examine the kinetics of the secondary response in an important immunological model, infection with attenuated Lis...

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發表在:Front Immunol
Main Authors: Malhotra, Deepali, Burrack, Kristina S., Jenkins, Marc K., Frosch, Anne E.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492679/
https://ncbi.nlm.nih.gov/pubmed/32983171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02125
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