Heterologous Boosting With Listeria-Based Recombinant Strains in BCG-Primed Mice Improved Protection Against Pulmonary Mycobacterial Infection

While Baccillus Calmette-Guerin (BCG) is used worldwide, tuberculosis (TB) is still a global concern due to the poor efficacy of BCG. Novel vaccine candidates are therefore urgently required. In this study, two attenuated recombinant Listeria strains, LMΔ-msv and LIΔ-msv were constructed by deletion...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Liu, Si-Jing, Tian, Si-Cheng, Zhang, Yun-Wen, Tang, Tian, Zeng, Ju-Mei, Fan, Xiao-Yong, Wang, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492678/
https://ncbi.nlm.nih.gov/pubmed/32983151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02036
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