Metformin attenuates cadmium-induced neuronal apoptosis in vitro via blocking ROS-dependent PP5/AMPK-JNK signaling pathway

Cadmium (Cd), a toxic environment contaminant, induces reactive oxygen species (ROS)-mediated neuronal apoptosis and consequential neurodegenerative disorders. Metformin, an anti-diabetic drug, has recently received a great attention owing to its protection against neurodegenerative diseases. Howeve...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Chen, Xiaoling, Wu, Wen, Gong, Baoming, Hou, Long, Dong, Xiaoqing, Xu, Chong, Zhao, Rui, Yu, Qianyun, Zhou, Zhihan, Huang, Shile, Chen, Long
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492486/
https://ncbi.nlm.nih.gov/pubmed/32209321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.108065
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