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Ensemble forecast modeling for the design of COVID-19 vaccine efficacy trials

To rapidly evaluate the safety and efficacy of COVID-19 vaccine candidates, prioritizing vaccine trial sites in areas with high expected disease incidence can speed endpoint accrual and shorten trial duration. Mathematical and statistical forecast models can inform the process of site selection, int...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Dean, Natalie E., Pastore y Piontti, Ana, Madewell, Zachary J., Cummings, Derek A.T, Hitchings, Matthew D.T., Joshi, Keya, Kahn, Rebecca, Vespignani, Alessandro, Halloran, M. Elizabeth, Longini, Ira M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492005/
https://ncbi.nlm.nih.gov/pubmed/33012602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.09.031
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