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Ensemble forecast modeling for the design of COVID-19 vaccine efficacy trials

To rapidly evaluate the safety and efficacy of COVID-19 vaccine candidates, prioritizing vaccine trial sites in areas with high expected disease incidence can speed endpoint accrual and shorten trial duration. Mathematical and statistical forecast models can inform the process of site selection, int...

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Bibliographic Details
Published in:Vaccine
Main Authors: Dean, Natalie E., Pastore y Piontti, Ana, Madewell, Zachary J., Cummings, Derek A.T, Hitchings, Matthew D.T., Joshi, Keya, Kahn, Rebecca, Vespignani, Alessandro, Halloran, M. Elizabeth, Longini, Ira M.
Format: Artigo
Language:Inglês
Published: Elsevier Ltd. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492005/
https://ncbi.nlm.nih.gov/pubmed/33012602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.09.031
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