Mutations in the anti-sigma H factor RshA confer resistance to econazole and clotrimazole in Mycobacterium smegmatis

Azole drugs such as econazole, are active on Mycobacterium tuberculosis and Mycobacterium smegmatis ; however, the identification of their target(s) is still pending. It has been reported that mutations in the non-essential system mmpL5-mmpS5 conferred resistance to econazole in M. tuberculosis . We...

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Udgivet i:Access Microbiol
Main Authors: Morbidoni, Héctor R., de la Iglesia, Agustina I., Figueroa, Virginia, Di Capua, Cecilia, Ioerger, Thomas R., Parish, Tanya
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2019
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491931/
https://ncbi.nlm.nih.gov/pubmed/32974504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/acmi.0.000070
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