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Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton
Neutrophils rely on glycolysis for energy production. How mitochondria regulate neutrophil function is not fully understood. Here, we report that mitochondrial outer membrane protein Mitofusin 2 (MFN2) regulates neutrophil homeostasis and chemotaxis in vivo. Mfn2-deficient neutrophils are released f...
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| Veröffentlicht in: | J Cell Sci |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7491649/ https://ncbi.nlm.nih.gov/pubmed/32788232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248880 |
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