Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro

SARS-CoV-2 primarily infects cells at mucosal surfaces. Serum neutralizing antibody responses are variable and generally low in individuals that suffer mild forms of the illness. Although potent IgG antibodies can neutralize the virus, less is known about secretory antibodies such as IgA that might...

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Publicado en:bioRxiv
Autores principales: Wang, Zijun, Lorenzi, Julio C. C., Muecksch, Frauke, Finkin, Shlomo, Viant, Charlotte, Gaebler, Christian, Cipolla, Melissa, Hoffman, Hans-Heinrich, Oliveira, Thiago Y., Oren, Deena A., Ramos, Victor, Nogueira, Lilian, Michailidis, Eleftherios, Robbiani, Davide F., Gazumyan, Anna, Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491508/
https://ncbi.nlm.nih.gov/pubmed/32935095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.09.288555
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