Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

The emergence of SARS-CoV-2 and the ensuing explosive epidemic of COVID-19 disease has generated a need for assays to rapidly and conveniently measure the antiviral activity of SARS-CoV-2–specific antibodies. Here, we describe a collection of approaches based on SARS-CoV-2 spike-pseudotyped, single-...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Hoffmann, Hans-Heinrich, Michailidis, Eleftherios, Lorenzi, Julio C.C., Mendoza, Pilar, Rutkowska, Magdalena, Bednarski, Eva, Gaebler, Christian, Agudelo, Marianna, Cho, Alice, Wang, Zijun, Gazumyan, Anna, Cipolla, Melissa, Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2020
Sujets:
Technical Advances and Resources
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372514/
https://ncbi.nlm.nih.gov/pubmed/32692348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201181
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