Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

The emergence of SARS-CoV-2 and the ensuing explosive epidemic of COVID-19 disease has generated a need for assays to rapidly and conveniently measure the antiviral activity of SARS-CoV-2–specific antibodies. Here, we describe a collection of approaches based on SARS-CoV-2 spike-pseudotyped, single-...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Hoffmann, Hans-Heinrich, Michailidis, Eleftherios, Lorenzi, Julio C.C., Mendoza, Pilar, Rutkowska, Magdalena, Bednarski, Eva, Gaebler, Christian, Agudelo, Marianna, Cho, Alice, Wang, Zijun, Gazumyan, Anna, Cipolla, Melissa, Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
Soggetti:
Technical Advances and Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372514/
https://ncbi.nlm.nih.gov/pubmed/32692348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201181
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