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Adiponectin Receptor Agonist AdipoRon Induces Apoptotic Cell Death and Suppresses Proliferation in Human Ovarian Cancer Cells

OBJECTIVES: We tested the hypothesis that stimulation of adiponectin receptors with the synthetic agonist AdipoRon suppresses proliferation and induces apoptotic death in human high grade serous ovarian tumor cell lines and in ex vivo primary tumors, mediated by activation of 5’ AMP-activated protei...

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Detalhes bibliográficos
Publicado no:Mol Cell Biochem
Main Authors: Ramzan, Amin A., Bitler, Benjamin G., Hicks, Douglas, Barner, Kelsey, Qamar, Lubna, Behbakht, Kian, Powell, Theresa, Jansson, Thomas, Wilson, Heidi
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490954/
https://ncbi.nlm.nih.gov/pubmed/31292831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-019-03586-9
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