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miR-148a Affects Polarization of THP-1-Derived Macrophages and Reduces Recruitment of Tumor-Associated Macrophages via Targeting SIRPα

PURPOSE: The objective of this study was to investigate the effect of miR-148a on the polarization and recruitment of tumor-associated macrophages (TAMs). METHODS: In human monocyte THP-1 cells, M1 or M2 differentiation was induced by phorbol 12-myristate 13-acetate (PMA) with specific induction sup...

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Publicat a:Cancer Manag Res
Autors principals: Ma, Donghe, Zhang, Yan, Chen, Guanghua, Yan, Jia
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490441/
https://ncbi.nlm.nih.gov/pubmed/32982404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S238317
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