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miR-148a Affects Polarization of THP-1-Derived Macrophages and Reduces Recruitment of Tumor-Associated Macrophages via Targeting SIRPα

PURPOSE: The objective of this study was to investigate the effect of miR-148a on the polarization and recruitment of tumor-associated macrophages (TAMs). METHODS: In human monocyte THP-1 cells, M1 or M2 differentiation was induced by phorbol 12-myristate 13-acetate (PMA) with specific induction sup...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Ma, Donghe, Zhang, Yan, Chen, Guanghua, Yan, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490441/
https://ncbi.nlm.nih.gov/pubmed/32982404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S238317
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