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Caveolin-1 Promotes Cellular Senescence in Exchange for Blocking Subretinal Fibrosis in Age-Related Macular Degeneration
PURPOSE: To determine whether caveolin-1 (i) prevents epithelial–mesenchymal transition in the RPE and laser-induced subretinal fibrosis and (ii) promotes or inhibits cellular senescence in the RPE. METHODS: We examined laser-induced subretinal fibrosis and RPE cell contraction in wild-type and Cave...
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| Опубликовано в: : | Invest Ophthalmol Vis Sci |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Association for Research in Vision and Ophthalmology
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7490224/ https://ncbi.nlm.nih.gov/pubmed/32926104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.11.21 |
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