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Caveolin-1 Promotes Cellular Senescence in Exchange for Blocking Subretinal Fibrosis in Age-Related Macular Degeneration
PURPOSE: To determine whether caveolin-1 (i) prevents epithelial–mesenchymal transition in the RPE and laser-induced subretinal fibrosis and (ii) promotes or inhibits cellular senescence in the RPE. METHODS: We examined laser-induced subretinal fibrosis and RPE cell contraction in wild-type and Cave...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7490224/ https://ncbi.nlm.nih.gov/pubmed/32926104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.11.21 |
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