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Complement activation and thrombin generation by MBL bound to beta2-glycoprotein I

Beta2-glycoprotein I (β2-GPI) is an abundant plasma glycoprotein with unknown physiological function and is currently recognized as the main target of anti-phospholipid antibodies responsible for complement activation and vascular thrombosis in patients with anti-phospholipid syndrome (APS). Here, w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Durigutto, Paolo, Macor, Paolo, Pozzi, Nicola, Agostinis, Chiara, Bossi, Fleur, Meroni, PierLuigi, Grossi, Claudia, Borghi, Maria O., Planer, William, Garred, Peter, Tedesco, Francesco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489996/
https://ncbi.nlm.nih.gov/pubmed/32759297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000570
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