Glymphatic system impairment in Alzheimer’s disease and idiopathic normal pressure hydrocephalus

~10% of dementia patients have idiopathic normal pressure hydrocephalus (iNPH), an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and Alzheimer’s disease (AD) both exhibit sleep disturbances, build-up of brain metabolic wastes and Aβ plaques, perivascular reactive astroglio...

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Publicado en:Trends Mol Med
Autores principales: Reeves, Benjamin C., Karimy, Jason K., Kundishora, Adam J., Mestre, Humberto, Cerci, H. Mert, Matouk, Charles, Alper, Seth L., Lundgaard, Iben, Nedergaard, Maiken, Kahle, Kristopher T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489754/
https://ncbi.nlm.nih.gov/pubmed/31959516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.11.008
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