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Thymoquinone and Difluoromethylornithine (DFMO) Synergistically Induce Apoptosis of Human Acute T Lymphoblastic Leukemia Jurkat Cells Through the Modulation of Epigenetic Pathways

Thymoquinone (TQ), a natural anticancer agent exerts cytotoxic effects on several tumors by targeting multiple pathways, including apoptosis. Difluoromethylornithine (DFMO), an irreversible inhibitor of the ornithine decarboxylase (ODC) enzyme, has shown promising inhibitory activities in many cance...

詳細記述

保存先:
書誌詳細
出版年:Technol Cancer Res Treat
主要な著者: Alhosin, Mahmoud, Razvi, Syed Shoeb I., Sheikh, Ryan A., Khan, Jalaluddin A., Zamzami, Mazin A., Choudhry, Hani
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488875/
https://ncbi.nlm.nih.gov/pubmed/32912061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1533033820947489
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