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HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway

BACKGROUND: Hexokinase domain component 1 (HKDC1) plays an oncogenic role in certain types of cancer, such as lymphoma, liver cancer, and breast cancer. Previous bioinformatics study revealed that HKDC1 was significantly upregulated in lung adenocarcinoma (LUAD). However, its biological functions an...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Wang, Xinyu, Shi, Bowen, Zhao, Yue, Lu, Qijue, Fei, Xiang, Lu, Chaojing, Li, Chunguang, Chen, Hezhong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488676/
https://ncbi.nlm.nih.gov/pubmed/32943998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01539-7
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