HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway

BACKGROUND: Hexokinase domain component 1 (HKDC1) plays an oncogenic role in certain types of cancer, such as lymphoma, liver cancer, and breast cancer. Previous bioinformatics study revealed that HKDC1 was significantly upregulated in lung adenocarcinoma (LUAD). However, its biological functions an...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Wang, Xinyu, Shi, Bowen, Zhao, Yue, Lu, Qijue, Fei, Xiang, Lu, Chaojing, Li, Chunguang, Chen, Hezhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488676/
https://ncbi.nlm.nih.gov/pubmed/32943998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01539-7
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