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HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway

BACKGROUND: Hexokinase domain component 1 (HKDC1) plays an oncogenic role in certain types of cancer, such as lymphoma, liver cancer, and breast cancer. Previous bioinformatics study revealed that HKDC1 was significantly upregulated in lung adenocarcinoma (LUAD). However, its biological functions an...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Wang, Xinyu, Shi, Bowen, Zhao, Yue, Lu, Qijue, Fei, Xiang, Lu, Chaojing, Li, Chunguang, Chen, Hezhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488676/
https://ncbi.nlm.nih.gov/pubmed/32943998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01539-7
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