Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington’s disease transgenic mouse

BACKGROUND: Huntington’s disease (HD) is a neurodegenerative disease that involves a complex combination of psychiatric, cognitive and motor impairments. Synaptic dysfunction has been implicated in HD pathogenesis. However, the mechanisms have not been clearly delineated. Synaptic vesicular zinc is...

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Udgivet i:Cell Biosci
Main Authors: Niu, Li, Li, Li, Yang, Shiming, Wang, Weixi, Ye, Cuifang, Li, He
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488477/
https://ncbi.nlm.nih.gov/pubmed/32944220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00459-3
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