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Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene

The mammalian protein ZnT3 resides on synaptic vesicle membranes of zinc-containing neurons, suggesting its possible role in vesicular zinc transport. We show here that histochemically reactive zinc, corresponding to the zinc found within synaptic vesicles, was undetectable in the brains of mice wit...

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Detalhes bibliográficos
Main Authors: Cole, Toby B., Wenzel, H. Jürgen, Kafer, Kathy E., Schwartzkroin, Philip A., Palmiter, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15571/
https://ncbi.nlm.nih.gov/pubmed/9990090
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