Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development

BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and sulindac are effective for colorectal cancer prevention in humans and some animal models, but concerns over gastro-intestinal (GI) ulceration and bleeding limit their potential for chemopreventive use in broader populatio...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Davis, Jennifer S., Kanikarla-Marie, Preeti, Gagea, Mihai, Yu, Patrick L., Fang, Dexing, Sebastian, Manu, Yang, Peiying, Hawk, Ernest, Dashwood, Roderick, Lichtenberger, Lenard M., Menter, David, Kopetz, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488444/
https://ncbi.nlm.nih.gov/pubmed/32912193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07311-4
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