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Metalign: efficient alignment-based metagenomic profiling via containment min hash

Metagenomic profiling, predicting the presence and relative abundances of microbes in a sample, is a critical first step in microbiome analysis. Alignment-based approaches are often considered accurate yet computationally infeasible. Here, we present a novel method, Metalign, that performs efficient...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: LaPierre, Nathan, Alser, Mohammed, Eskin, Eleazar, Koslicki, David, Mangul, Serghei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488264/
https://ncbi.nlm.nih.gov/pubmed/32912225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02159-0
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