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Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells

Circulating tumor cells (CTCs) are shed from solid cancers in the form of single or clustered cells, and the latter display an extraordinary ability to initiate metastasis. Yet, the biological phenomena that trigger the shedding of CTC clusters from a primary cancerous lesion are poorly understood....

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Bibliographic Details
Published in:Cell Rep
Main Authors: Donato, Cinzia, Kunz, Leo, Castro-Giner, Francesc, Paasinen-Sohns, Aino, Strittmatter, Karin, Szczerba, Barbara Maria, Scherrer, Ramona, Di Maggio, Nunzia, Heusermann, Wolf, Biehlmaier, Oliver, Beisel, Christian, Vetter, Marcus, Rochlitz, Christoph, Weber, Walter Paul, Banfi, Andrea, Schroeder, Timm, Aceto, Nicola
Format: Artigo
Language:Inglês
Published: Cell Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487783/
https://ncbi.nlm.nih.gov/pubmed/32905777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108105
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