Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

The ability of circulating tumor cells (CTCs) to form clusters has been linked to increased metastatic potential. Yet biological features and vulnerabilities of CTC clusters remain largely unknown. Here, we profile the DNA methylation landscape of single CTCs and CTC clusters from breast cancer pati...

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Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Gkountela, Sofia, Castro-Giner, Francesc, Szczerba, Barbara Maria, Vetter, Marcus, Landin, Julia, Scherrer, Ramona, Krol, Ilona, Scheidmann, Manuel C., Beisel, Christian, Stirnimann, Christian U., Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Aceto, Nicola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363966/
https://ncbi.nlm.nih.gov/pubmed/30633912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.046
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