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Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis

Circulating tumor cells (CTCs) are defined as those cells that detach from a cancerous lesion and enter the bloodstream. While generally most CTCs are subjected to high shear stress, anoikis signals, and immune attack in the circulatory system, few are able to survive and reach a distant organ in a...

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Pubblicato in:Front Med (Lausanne)
Autori principali: Castro-Giner, Francesc, Scheidmann, Manuel C., Aceto, Nicola
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827555/
https://ncbi.nlm.nih.gov/pubmed/29520361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00034
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