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Statistically efficient association analysis of quantitative traits with haplotypes and untyped SNPs in family studies

BACKGROUND: Associations between haplotypes and quantitative traits provide valuable information about the genetic basis of complex human diseases. Haplotypes also provide an effective way to deal with untyped SNPs. Two major challenges arise in haplotype-based association analysis of family data. F...

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Bibliografiske detaljer
Udgivet i:BMC Genet
Main Authors: Diao, Guoqing, Lin, Dan-yu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487716/
https://ncbi.nlm.nih.gov/pubmed/32894040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00902-x
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