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Statistically efficient association analysis of quantitative traits with haplotypes and untyped SNPs in family studies

Abstract Background Associations between haplotypes and quantitative traits provide valuable information about the genetic basis of complex human diseases. Haplotypes also provide an effective way to deal with untyped SNPs. Two major challenges arise in haplotype-based association analysis of family...

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Main Authors: Guoqing Diao, Dan-yu Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-09-01
Colecção:BMC Genetics
Assuntos:
Acesso em linha:http://link.springer.com/article/10.1186/s12863-020-00902-x
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