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Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo
BACKGROUND: Alpha-1 antitrypsin deficiency (AATD)-mediated liver disease is a toxic “gain-of-function” inflammation in the liver associated with intracellular retention of mutant alpha-1 antitrypsin. The clinical presentation of the disease includes fibrosis, cirrhosis and liver failure. However, th...
में बचाया:
| में प्रकाशित: | Cell Commun Signal |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7487708/ https://ncbi.nlm.nih.gov/pubmed/32887613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00648-0 |
| टैग : |
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