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In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

BACKGROUND: Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CDPS)-dependent pathways, in which they play an early role i...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Le Chevalier, Fabien, Correia, Isabelle, Matheron, Lucrèce, Babin, Morgan, Moutiez, Mireille, Canu, Nicolas, Gondry, Muriel, Lequin, Olivier, Belin, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487605/
https://ncbi.nlm.nih.gov/pubmed/32894164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01432-y
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