Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm

Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca(2+) influx via the sperm-specific, pH-sensitive Ca(2+) channel CatSper. However, the physiological role and molecular mechanisms underlying Z...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Balbach, Melanie, Hamzeh, Hussein, Jikeli, Jan F., Brenker, Christoph, Schiffer, Christian, Hansen, Jan N., Neugebauer, Pia, Trötschel, Christian, Jovine, Luca, Han, Ling, Florman, Harvey M., Kaupp, U. Benjamin, Strünker, Timo, Wachten, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487327/
https://ncbi.nlm.nih.gov/pubmed/32984353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.572735
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