A novel biosensor to study cAMP dynamics in cilia and flagella

The cellular messenger cAMP regulates multiple cellular functions, including signaling in cilia and flagella. The cAMP dynamics in these subcellular compartments are ill-defined. We introduce a novel FRET-based cAMP biosensor with nanomolar sensitivity that is out of reach for other sensors. To meas...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Mukherjee, Shatanik, Jansen, Vera, Jikeli, Jan F, Hamzeh, Hussein, Alvarez, Luis, Dombrowski, Marco, Balbach, Melanie, Strünker, Timo, Seifert, Reinhard, Kaupp, U Benjamin, Wachten, Dagmar
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811770/
https://ncbi.nlm.nih.gov/pubmed/27003291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14052
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki