A novel biosensor to study cAMP dynamics in cilia and flagella

The cellular messenger cAMP regulates multiple cellular functions, including signaling in cilia and flagella. The cAMP dynamics in these subcellular compartments are ill-defined. We introduce a novel FRET-based cAMP biosensor with nanomolar sensitivity that is out of reach for other sensors. To meas...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Mukherjee, Shatanik, Jansen, Vera, Jikeli, Jan F, Hamzeh, Hussein, Alvarez, Luis, Dombrowski, Marco, Balbach, Melanie, Strünker, Timo, Seifert, Reinhard, Kaupp, U Benjamin, Wachten, Dagmar
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811770/
https://ncbi.nlm.nih.gov/pubmed/27003291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14052
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker