Hepatic lipids promote liver metastasis

Obesity predisposes to cancer and a virtual universality of nonalcoholic fatty liver disease (NAFLD). However, the impact of hepatic steatosis on liver metastasis is enigmatic. We find that while control mice were relatively resistant to hepatic metastasis, those which were lipodystrophic or obese,...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Li, Yongjia, Su, Xinming, Rohatgi, Nidhi, Zhang, Yan, Brestoff, Jonathan R., Shoghi, Kooresh I., Xu, Yalin, Semenkovich, Clay F., Harris, Charles A., Peterson, Lindsay L., Weilbaecher, Katherine N., Teitelbaum, Steven L., Zou, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487169/
https://ncbi.nlm.nih.gov/pubmed/32879136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136215
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