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The N-terminal domain of Staphylothermus marinus McrB shares structural homology with PUA-like RNA binding proteins
McrBC is a conserved modification-dependent restriction system that in Escherichia coli specifically targets foreign DNA containing methylated cytosines. Crystallographic data show that the N-terminal domain of Escherichia coli McrB binds substrates via a base flipping mechanism. This region is poor...
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| 發表在: | J Struct Biol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7487167/ https://ncbi.nlm.nih.gov/pubmed/32652237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2020.107572 |
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