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The N-terminal domain of Staphylothermus marinus McrB shares structural homology with PUA-like RNA binding proteins

McrBC is a conserved modification-dependent restriction system that in Escherichia coli specifically targets foreign DNA containing methylated cytosines. Crystallographic data show that the N-terminal domain of Escherichia coli McrB binds substrates via a base flipping mechanism. This region is poor...

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Detalles Bibliográficos
Publicado en:J Struct Biol
Autores principales: Hosford, Christopher J., Adams, Myfanwy C., Niu, Yiming, Chappie, Joshua S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487167/
https://ncbi.nlm.nih.gov/pubmed/32652237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2020.107572
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