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In vivo imaging of calcium and glutamate responses to intracortical microstimulation reveals distinct temporal responses of the neuropil and somatic compartments in layer II/III neurons

OBJECTIVE: Intracortical microelectrode implants can generate a tissue response hallmarked by glial scarring and neuron cell death within 100–150 μm of the biomaterial device. Many have proposed that any performance decline in intracortical microstimulation (ICMS) due to this foreign body tissue res...

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Publicat a:Biomaterials
Autors principals: Eles, James R., Kozai, Takashi D.Y.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487166/
https://ncbi.nlm.nih.gov/pubmed/31954232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119767
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