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In vivo imaging of calcium and glutamate responses to intracortical microstimulation reveals distinct temporal responses of the neuropil and somatic compartments in layer II/III neurons
OBJECTIVE: Intracortical microelectrode implants can generate a tissue response hallmarked by glial scarring and neuron cell death within 100–150 μm of the biomaterial device. Many have proposed that any performance decline in intracortical microstimulation (ICMS) due to this foreign body tissue res...
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| Pubblicato in: | Biomaterials |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7487166/ https://ncbi.nlm.nih.gov/pubmed/31954232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119767 |
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