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In vivo imaging of calcium and glutamate responses to intracortical microstimulation reveals distinct temporal responses of the neuropil and somatic compartments in layer II/III neurons

OBJECTIVE: Intracortical microelectrode implants can generate a tissue response hallmarked by glial scarring and neuron cell death within 100–150 μm of the biomaterial device. Many have proposed that any performance decline in intracortical microstimulation (ICMS) due to this foreign body tissue res...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Eles, James R., Kozai, Takashi D.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487166/
https://ncbi.nlm.nih.gov/pubmed/31954232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119767
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