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An enumerative algorithm for de novo design of proteins with diverse pocket structures
To create new enzymes and biosensors from scratch, precise control over the structure of small-molecule binding sites is of paramount importance, but systematically designing arbitrary protein pocket shapes and sizes remains an outstanding challenge. Using the NTF2-like structural superfamily as a m...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7486743/ https://ncbi.nlm.nih.gov/pubmed/32839327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005412117 |
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