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Lopinavir-Ritonavir in SARS-CoV-2 Infection and Drug-Drug Interactions with Cardioactive Medications

Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A low dose of ritonavir is added to other protease inhibitors to take advantage of potent inhibition of cytochrome (CYP) P450 3A4, thereby significantly increasing the plasma concentration of coadministered lopi...

詳細記述

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書誌詳細
出版年:Cardiovasc Drugs Ther
主要な著者: Agarwal, Shubham, Agarwal, Sanjeev Kumar
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486594/
https://ncbi.nlm.nih.gov/pubmed/32918656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-020-07070-1
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