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Lopinavir-Ritonavir in SARS-CoV-2 Infection and Drug-Drug Interactions with Cardioactive Medications

Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A low dose of ritonavir is added to other protease inhibitors to take advantage of potent inhibition of cytochrome (CYP) P450 3A4, thereby significantly increasing the plasma concentration of coadministered lopi...

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Bibliografiska uppgifter
I publikationen:Cardiovasc Drugs Ther
Huvudupphovsmän: Agarwal, Shubham, Agarwal, Sanjeev Kumar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486594/
https://ncbi.nlm.nih.gov/pubmed/32918656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-020-07070-1
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