Direct Delivery of Apatite Nanoparticle-Encapsulated siRNA Targeting TIMP-1 for Intractable Abnormal Scars

Hypertrophic scars (HSs) and keloids are histologically characterized by excessive extracellular matrix (ECM) deposition. ECM deposition depends on the balance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteases (TIMPs). TIMP-1 has been linked to ECM degradation and is...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Nucleic Acids
Hoofdauteurs: Aoki, Masayo, Matsumoto, Noriko M., Dohi, Teruyuki, Kuwahawa, Hiroaki, Akaishi, Satoshi, Okubo, Yuri, Ogawa, Rei, Yamamoto, Hirofumi, Takabe, Kazuaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486579/
https://ncbi.nlm.nih.gov/pubmed/32911344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.08.005
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